Enalapril-induced acute kidney injury in neonates

Abstract. Angiotensin converting enzyme inhibitors have been used in the neonatal population for both cardiac and renal diseases. Past reports have described deleterious renal and neurological consequences as a result of these drugs. This report describes two infants receiving enalapril for different indications who suffered renal impairments, likely a result of concomitant diuretic use. These cases demonstrate the risks associated with ACE inhibitor use and the importance of vigilant monitoring when using these medications.

*Corresponding Author: 

Dr. Anne Russo, Division of Newborn Medicine N 506, New York Presbyterian Hospital, 525 East 68th Street, NY 10065, New York, USA. Tel.: +1 212 746 3530; E-mail: arusso319@gmail.com.