Fetal intestinal perforation and meconium peritonitis associated with maternal autoimmune hepatitis

P. Charlagorla, S. Sublett, F. Sy, E. Kessler, A. Gad∗ | JNPM 2014;

Abstract. Autoimmune hepatitis (AIH) in pregnancy can affect both fetal and maternal outcomes. Little is known regarding the fetal outcomes of AIH in pregnancy. The major risks include spontaneous abortions, fetal mortality, perinatal mortality and prematurity. Two common drugs used in the management of AIH, azathioprine and prednisone, may also be associated with adverse fetal outcomes. We present the case of perinatal focal intestinal perforation with a meconium pseudocyst in a preterm infant of a mother with autoimmune hepatitis on azathioprine and methylprednisone.

*Corresponding Author: 

Dr. Ashraf Gad, Division of Neonatology, NY Methodist Hospital, 506 6th street, Brooklyn, NY 11215, USA. Tel.: +1 718 780 5260; Fax: +1 718 780 3266; E-mail: imamgad@hotmail.com.