Umbilical cord and preeclampsia

M. Olaya-C*, J. Salcedo-Betancourt, S.H. Galvis, A.M. Ortiz, S. Gutierrez, J.E. Bernal | JNPM 2016;


INTRODUCTION:Preeclampsia is associated with abnormalities in the umbilical cord in several ways: morphological, biochemical and functional. Alteration in blood vessels of the placenta, decidua and circulatory system of the fetus might be related to factors that cause preeclampsia and may be associated with alterations of the umbilical cord.

OBJECTIVES:This study aimed to analyze the relationship between each type of umbilical cord abnormality and the different subtypes of hypertensive gestational disorders.

METHODS:We conducted a prospective study on consecutive autopsies and its placentas, looking for abnormalities in the umbilical cord’s features and their clinical associations.

RESULTS:Umbilical cord abnormalities including length, diameter, insertion, entanglements, knots and coils were associated with maternal gestational hypertension.

CONCLUSION:In women with gestational hypertension, umbilical cord abnormalities are associated with fetal and neonatal consequences.

*Corresponding Author: 

Mercedes Olaya-Contreras, MD, PhD, Department of Pathology, Pontificia Universidad Javeriana, the Medical School. Cra. 7 No. 40-62 - Hospital Universitario San Ignacio, Bogota, Colombia. Tel.: +571 594 6161/Ext: 2440; E-mails: